$7.01 (1%) as a Prime member. A serious hypersensitivity reaction can cause symptoms such as: When Ajovy is dispensed from the pharmacy, the pharmacist will add an expiration date to the label on the container. It can be given as a single injection of 225 mg once per month, or as three separate injections (for a total of 675 mg) once every three months. You are encouraged to report side effects to the FDA at 1-800-FDA-1088. You can also call the Shared Solutions hotline at 1-800-887-8100 to be connected with a nurse who can answer your questions. Ajovy also differs from most other migraine medications in that its injected once a month or once every three months. Ajovy and Aimovig are both FDA-approved to prevent migraine headaches in adults. No, Ajovy does not help cure migraine headaches. Your doctor will choose the right schedule for you. In addition, migraine treatment guidelines recommend either drug as an option for certain people. Quoted prices are for cash-paying customers and are not valid with insurance plans. You are about to leave AJOVY.com and enter a website operated by a third party. Sharps waste should be placed in a State approved container. When the needle clipper is full, it can be disposed of according to your state or local regulations. Be sure the alcohol is completely dry before you inject the drug. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. . Dont rub the area. How Viagra became a new 'tool' for young men, The amazing story of hepatitis C, from discovery to cure, Ankylosing Spondylitis Pain: Fact or Fiction, calcitonin gene-related peptide (CGRP) antagonists, calcitonin gene-related peptide (CGRP) antagonist, chronic migraine headaches and episodic migraine, Fast food consumption may increase the risk of liver disease. After injecting Ajovy, pull the needle straight out of the skin and release the fold of skin. However, be sure to take the dosage your doctor prescribes for you. If your symptoms feel life threatening or if you think youre having a medical emergency, call 911. Therefore, they have some similar side effects, and some different. Rivonia, Johannesburg Keep your sharps containers out of reach of children and pets. See full Terms and Conditions for eligibility and restrictions. (Fremanezumab is the active drug in Ajovy.). This may make it a good choice for people who cant take other drugs because of side effects or drug interactions. However, its still important to talk to your doctor or pharmacist about any prescription medications, vitamins, supplements, and over-the-counter medications you take before starting Ajovy. Next, wait about 10 seconds to make sure all the medicine is injected. Are you ahealthcare professional in the United States? If you can't get a sharps container, use a heavy-duty plastic household container with a tight-fitting lid, such as a laundry detergent bottle, to dispose of used sharps. Collection Center, Sunnyvale Materials Recovery and Transfer Station, Kern County Household Hazardous Waste Events-Tehachapi Sanitary Landfill (January 7th and January 21st Only), Los Angeles County Sheriff's Department-Temple Station, Torrance Health Center *FACILITY CLOSED DUE TO COVID-19*, Eastern Regional Materials Recovery Facility *Appointment Required*, Upland Household Hazardous Waste Collection Facility, Recology Vacaville Solano Recycling Center *CLOSED DUE TO COVID-19*, Recology Vacaville Solano Household Hazardous Waste Center, Recology Vallejo Household Hazardous Waste Center, San Diego County Sheriff's Department-Valley Center Substation, Victorville Household Hazardous Waste Facility, Vista Household Hazardous Waste Collection Center, Los Angeles County Sheriff's Department-Walnut/Diamond Bar Station, Los Angeles County Sheriff's Department-West Hollywood Station, West Sacramento At Your Door Service *Appointment Required*, Glenn County Public Health Department-Willows Office, Sonoma County Community Toxics Collection Event-Oakmont (March 14th Only), Siskiyou County Department of Public Health, Yuba-Sutter Household Hazardous Waste Facility, Chula Vista, Imperial Beach, National City, Unincorporated San Diego County, Costa Mesa, portions of Newport Beach,Unincorporated Orange County, Davis, El Macero, Rural Davis, Rural Yolo County, Willowbank, Elk Grove, Galt, Rancho Cordova, Sacramento, Sacramento County, Hollister, San Juan Bautista,Unincorporated San Benito County, Basset, Cypress, El Monte, Hacienda Heights, La Puente, San Jose Hills, Valinda, Walnut, Call or Visit Website for 2023 Event Dates, Camp Pendleton, Carlsbad, Del Mar,Oceanside, Solana Beach, Carlsbad, Del Mar, Encinitas, Escondido, National City, Poway, San Marcos, Santee, Solana Beach, Vista, Buellton, Carpinteria, Goleta, Santa Barbara, Solvang, Unincorporated Santa Barbara County, Carlsbad, Del Mar, Encinitas, Escondido, National City, Poway, San Marcos, Solana Beach, Vista. Most reactions were mild to moderate, but some led to discontinuation or required corticosteroid treatment. Ajovy is given as a subcutaneous injection. And these medications appear to be safe for most people. If youre giving yourself three injections, dont give yourself any injections in the same spot. Whether you are injecting your AJOVY quarterly or once monthly, the process is very similar. Ajovy and Emgality both stop the activity of calcitonin gene-related peptide (CGRP). Please note that SafeNeedleDisposal.org is not affiliated with these facilities or programs. This site is a project of NeedyMeds. It may take a few weeks for any migraine changes that Ajovy causes to become noticeable. These lists contain examples of more common side effects that can occur with Ajovy, with Aimovig, or with both drugs (when taken individually). One alternative drug is Botox. Its thought that this action helps prevent migraine headaches before they start. Botox has also been approved to treat many conditions, including: Ajovy comes as a prefilled single-dose syringe, as well as a prefilled single-dose autoinjector. Ajovy can be injected monthly or quarterly (once every three months). Common side effects of AJOVY include injection-site reactions. Place the autoinjector at a 90 angle against your skin at your chosen injection site. Also, dont shake the syringe. However, its still too soon to know how common this effect could be because Ajovy and Emgality were approved in 2018. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies. The cost for Ajovy subcutaneous solution (vfrm 225 mg/1.5 mL) is around $745 for a supply of 1.5 milliliters, depending on the pharmacy you visit. It is illegal to dispose of sharps in your trash. Many patients prefer autoinjectors over single-use syringes as they are easier to use and may cause less worry. They also include people who cant tolerate other medications because of side effects or drug interactions. Please read and follow the Instructions For Use before you start using your autoinjector for AJOVY and each time you get a refill. The Food and Drug Administration (FDA) approved Ajovy in September 2018. As with most drugs, some people can experience an allergic reaction after they take Ajovy. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. (optional), Which dosing option were you prescribed? However, you may be more likely to have a migraine episode if you stop taking Ajovy. Agoura Hills Door-To-Door Collection Events *Appointment Required*, San Diego County Sheriff's Department-Alpine Station, Los Angeles County Sheriff's Department-Altadena Station, Napa-Vallejo Household Hazardous Waste Collection Facility, Anaheim Household Hazardous Waste Collection Center, Riverside County Household Hazardous Waste Collection Events-Anza Transfer Station (April 8th and August 19th Only), Apple Valley Household Hazardous Waste Collection Center, Azusa Senior Center *Appointment Required*, Barstow Household Hazardous Waste Facility, Los Angeles County Household Hazardous Waste Collection Event-John Anson Ford Park (January 7th Only), Ben Lomond Transfer Station and Recycle Center, Riverside County Household Hazardous Waste Collection Events-Blythe Landfill (January 28th and October 21st Only), Bonita Sunnyside Fire Department Station #38, San Diego County Sheriff's Department-Borrego Springs Office, Brawley Household Hazardous Waste Facility (Bi-Weekly), Mono County Environmental Health Department-Bridgeport Office, Shasta County Health and Human Services Agency-Burney, Los Angeles County Sheriff's Department-Malibu/Lost Hills Station, Calexico Household Hazardous Waste Facility (Bi-Weekly), San Diego County Sheriff's Department-Campo Substation, Carlsbad Waste Management Buy Back Center, Los Angeles County Sheriff's Department-Carson Station, Riverside County Household Hazardous Waste Collection Events-Edom Hill Transfer Station (February 11th, May 13th, September 16th and December 9th Only), Butte Regional Household Hazardous Waste Facility, Chula Vista Household Hazardous Waste Collection Center, Citrus Heights Door-to-Door Sharps Collection Program *Appointment Required*, Sonoma County Community Toxics Collection Event-Santa Rosa (January 17th Only), Riverside County Household Hazardous Waste Collection Events-Bagdouma Park Swim Center Parking Lot (February 11th and September 30th Only), Los Angeles County Sheriff's Department-Compton Station, Riverside County Household Hazardous Waste Collection Events-Corona City Hall Parking Lot (March 25th, March 26th, October 14th and October 15th Only), Coronado Household Hazardous Waste Collection Events-Public Services Facility (2nd and 4th Saturday of the month Only), Costa Mesa Sanitary District *CLOSED DUE TO COVID-19*, Costa Mesa Door-to-Door Collection *Appointment Required*, Sonoma County Community Toxics Collection Event-Cotati (February 14th Only), Santa Clara County Sheriff's Office-West Valley Division, Kaiser Permanente Medical Offices-Daly City, Dana Point Household Hazardous Waste Pick Up Service *Appointment Required*, Riverside County Household Hazardous Waste Collection Event-Desert Center Landfill (February 2nd Only), Diamond Bar At Your Door Service *Appointment Required*, Eastvale At Your Door Service *Appointment Required*, El Centro Household Hazardous Waste Facility, Los Angeles County Household Hazardous Waste Collection Event-Raytheon Company (January 14th Only), Elk Grove Sharps Pickup Program *Appointment Required*, Elk Grove Special Waste Collection Center, San Diego County Sheriff's Department-North Coastal Substation, Escondido Disposal *CLOSED DUE TO COVID-19*, Republic Services Household Hazardous Waste Program *Appointment Required*, Fallbrook Recycling and Transfer Station *FACILITY CLOSED DUE TO COVID-19*, San Diego County Sheriff's Department-Fallbrook Substation, Firebaugh Senior Center *CLOSED DUE TO COVID-19*, Folsom Fire Department Station #35 *Appointment Required*, Fontana Household Hazardous Waste Facility, Fremont Household Hazardous Waste Facility, Fresno Police Department-Northwest Station, Fresno Police Department-Northeast Station, Fresno Police Department-Downtown Station, Hayward Household Hazardous Waste Facility *Appointment Required*, Sonoma County Community Toxics Collection Event-Healsburg (February 7th Only), Huntington Beach Household Hazardous Waste Collection Center, Riverside County Household Hazardous Waste Collection Events-County Road Yard (May 13th and September 23rd Only), San Diego County Sheriff's Department-Imperial Beach Substation, Indian Wells Sharps Pick-Up Service *Appointment Required*, CVS Pharmacy #9648 Sharps Mail-Back Program, Riverside County Household Hazardous Waste Collection Events-City of Indio Corporate Yard (March 11th and December 9th Onlly), Los Angeles County Sheriff's Department-Industry Station, Valley Vista Services Sharps Mail-Back Program, Curtis R. Tucker Health Center *FACILITY CLOSED DUE TO COVID-19*, Irvine Household Hazardous Waste Collection Center, Joshua Tree Household Hazardous Waste Facility (Monthly), San Diego County Sheriff's Department-Julian Substation, Sonoma County Community Toxics Collection Event-Kenwood (February 28th Only), Fresno County Regional Household Hazardous Waste Facility, Los Angeles County Sheriff's Department-La Crescenta Station, Riverside County Household Hazardous Waste Collection Events-South City Hall Parking Lot (February 25th and November 18th Only), Lake Elsinore Department of Public Works (Monthly), San Diego County Sheriff's Department-Lakeside Substation, Los Angeles County Sheriff's Department-Lakewood Station, Los Angeles County Sheriff's Department-Lancaster Station, Sonoma County Community Toxics Collection Event-Larkfield (February 21st Only), Western Placer Waste Management Authority Household Hazardous Waste Facility, Livermore Household Hazardous Waste Facility *Appointment Required*, Los Angeles County Sheriff's Department-Lomita Station, Los Altos Police Department *Appointment Required*, Washington Blvd. CGRP causes vasodilation (widening of blood vessels) and inflammation in the brain. Im here to walk you through some instructions on how to use the autoinjector for AJOVY. Ajovy can be injected into three possible areas: the front of your thighs, the back of your upper arms, or your belly. To inject your dose of AJOVY, first clean the chosen injection area using a new alcohol swab and let your skin dry. Ajovy syringes and autoinjectors should be stored in the refrigerator in the original container to protect them from light. It alerts doctors and patients about drug effects that may be dangerous. Ajovy is a brand-name prescription medication that's used to prevent migraine headaches in adults. Your body can create antibodies to any foreign substance. Step 1: Place all needles and other sharps in a sharps disposal container immediately after they have been used. In clinical trials for both drugs, a small percentage of people experienced an immune reaction. It can be taken at any time of the day. Begin here, *Two Human Factor studies assessed evaluators' ability to complete critical tasks in order to demonstrate use of the AJOVY Autoinjector in simulated-use sessions. Many of these drugs are used off-label to help prevent migraine headaches. If Ajovy is stored outside of the refrigerator for 24 hours without being used, dont put it back into the refrigerator. Talk to your doctor about stopping AJOVY if you have an allergic reaction. AJOVY is a prescription medicine used for the preventive treatment of migraine in adults. AJOVY (fremanezumab-vfrm) injection is a sterile, preservative-free, clear to opalescent, colorless to slightly yellow solution for subcutaneous injection, supplied in a single-dose 225 mg/1.5 mL prefilled autoinjector and a single-dose 225 mg/1.5 mL prefilled syringe. Do not place your sharps waste in the trash, green waste, or recycling bin. Emgality is currently on backorder and I just had my first period since being off of it. For the county programs, services are restricted to residents of the county that sponsors the program. If youre prescribed 225 mg monthly, you will give yourself one injection. AJOVY may be administered in office by a healthcare professional or at home by the patient or caregiver.1 AJOVY is available in an autoinjector. Botox is given as an intramuscular injection, and its always given in a doctors office. This video does not replace the complete Instructions For Use included with your autoinjector. TEVA Shared Solutions (AJOVY): Contact program : Medications: container for ajovy sharps disposal container (Ajovy) Disposal Container : Eligibility Requirements : Insurance Status: Contact program for details. Its also available as a prefilled single-dose autoinjector. Ajovy hasnt been shown to interact with other medications. Its also available as a prefilled single-dose autoinjector. The migraine drugs that are available can help prevent or treat migraine headaches. Receptors are molecules on the walls of your brain cells. Be sure to check that AJOVY appears on the autoinjector and that the expiration date has not passed. Individuals requiring reasonable For more information on the two forms of Ajovy, see Drug forms and strengths in the Ajovy dosage section below. The information on this site is intended for healthcare professionals in the United States. When Ajovy was given to pregnant females in animal studies, no risk was shown to the pregnancy. This includes monoclonal antibodies such as Ajovy and Emgality. There a number of options available for use as sharps containers: Plastic, purpose-made sharps boxes; Thick cardboard sharps boxes which have been made water resistant; Plastic disc to place on a drinks can; Re-use a local container The American Academy of Neurology recommends Botox as a treatment option for people with chronic migraine headaches. The drugs Ajovy and Aimovig both come in the form of an injection thats given as a subcutaneous injection. You are about to leave AJOVYhcp.com and enter a website operated by a third party. You can self-inject the drug at home, or a healthcare professional can give you the injection at your doctors office. We also supply various different items. Now, pick up your autoinjector with one hand and pull the protective cap straight off with the other. As with all medications, Ajovy injection costs can vary. Migraine headaches may improve after menopause, but they may also get worse. But a 140-mg monthly dose may be better for some people. The more common side effects of Ajovy are injection site reactions. After about 15 seconds, you will hear a second "CLICK.". Beginning on September 1, 2008, State law (Section 118286 of the California Health and Safety Code) makes it illegal to dispose of home-generated sharps waste in the trash or recycling containers, and requires that all sharps waste be transported to a collection center in a sharps containers or other containers approved by the enforcement agency.. All Rights Reserved. This site is intended for US Healthcare Professionals only. More information can be found here. CGRP is a protein in your body. This chart compares some information about Ajovy, Aimovig, Emgality, and Vyepti. I was on emgality for over a year, and now this morning I have woken up with the heaviest period that I have had since before I was on it. Botox works by temporarily paralyzing the muscles into which its injected. This allows the drug to warm up and come to room temperature. If youd like to find an alternative to Ajovy, talk with your doctor. Most other drugs used to prevent migraine headaches come as tablets that you need to take once each day. The cost of either Ajovy or Emgality may vary depending on your treatment plan. Learn about dosage and more. The first time you get a prescription for Ajovy, your healthcare professional can explain how to inject the medication yourself. The results of clinical studies showed that many people who took Ajovy experienced fewer migraine days within one month of taking their first dose. Deep meditation: Might it change the gut microbiome to boost health? Cases of anaphylaxis and angioedema have been reported in the postmarketing setting. If the liquid has any particles in it or is discolored, cloudy or frozen, do not use the autoinjector and call your healthcare provider or pharmacist. Ajovy helps keep a migraine headache from starting by halting the activity of CGRP. Call your doctor for medical advice about side effects. Home-generated sharps waste is hypodermic needles, pen needles, intravenous needles, lancets, and other devices that are For other information, video, and images of injection instructions, see the manufacturers website. The FDA has approved Ajovy to prevent chronic or episodic migraine headaches in adults. Ajovy (fremanezumab-vfrm) is a medicine used to help prevent migraine headache attacks in adults 18 years of age and older. If youre on a quarterly schedule, administer the next dose 12 weeks after your makeup dose. Over several months, the number of migraine days continued to decrease for people in the study. Out-of-pocket costs may vary based on insurance coverage. These are not all the possible side effects of AJOVY. Alright, there you have it. Guidance on proper subcutaneous techniques should be provided. And people in this study didnt report any serious or long-term side effects. Requests should be made at least one week in advance to ensure availability. People who have chronic migraine headaches, on the other hand, experience 15 or more headache days each month over at least 3 months. Hypersensitivity Reactions: Hypersensitivity reactions, including rash, pruritus, drug hypersensitivity, and urticaria were reported with AJOVY in clinical trials. Both Ajovy and Emgality can be injected into three possible areas: the front of your thighs, the back of your upper arms, or your belly. Do not use AJOVY if you are allergic to AJOVY or any of the ingredients in AJOVY. Please note, this offer is not available for patients eligible for Medicare, Medicaid, or any other public payer coverage. You can self-inject Ajovy and Emgality at home. The County offers a mail-back Sharps Waste disposal program that is limited to ONLY elderly and disabled residents. As a result, there may be fewer drug interactions and side effects with Ajovy. The autoinjector and prefilled syringes both come in the same strength: 225 mg per 1.5 mL solution. If a hypersensitivity reaction occurs, consider discontinuing AJOVY and institute appropriate therapy. References: 1. If you think youve taken too much of this drug, call your doctor. You will hear a second click. A boxed warning is the strongest warning the FDA requires. Below are comparisons between Ajovy and several medications. Stopping Ajovy probably wont cause withdrawal symptoms. Or, you can inject on the fleshy areas at the back of either of your upper arms but you may need someone who has been instructed on how to give your injection to help you. Most counties in California have disposal programs. (The very first months dose is a two-injection dose totaling 240 mg.). Do not warm up the AJOVY prefilled autoinjector using a heat source such as hot water or a microwave, Keep AJOVY prefilled autoinjector out of the reach of small children, After you remove the protective cap from AJOVY, to prevent infection, do not touch the needle. Ajovy can be given as one injection of 225 mg once a month. Ajovy was the second drug in the CGRP antagonist class that the FDA approved to help prevent migraine headaches. This keeps CGRP from attaching to them. There are other drugs available that can help prevent migraine episodes. Click here for information on pharmaceutical company takeback programs. Ajovy helps prevent migraine headaches by halting the activity of certain proteins that trigger migraines. With one hand, firmly pull the cap straight off the autoinjector (dont twist) and throw the cap away immediately. READ FULL INSTRUCTIONS FOR USE FOR AUTOINJECTOR, READ FULL INSTRUCTIONS FOR USE FOR PREFILLED SYRINGE, Please see full Prescribing Information for AJOVY, AJOVY prefilled autoinjector is for single time (one-time) use only. Its okay if there are bubbles. No, Ajovy is not a treatment for migraine headaches. ", 97% in study 1 (N=30) and 98% in study 2 (N=47) answered "Yes".1. Contraindications: AJOVY is contraindicated in patients with serious hypersensitivity to fremanezumab-vfrm or to any of the excipients. The main drug ingredient in Botox is onabotulinumtoxinA. MNT is the registered trade mark of Healthline Media. You can inject the drugs yourself at home. If needed, contact your doctor about getting a new one. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. This drug is part of a class of drugs known as neurotoxins. Ajovy can cause mild or serious side effects. Details. Please see the Patient Information Leaflet within the full Prescribing Information at AJOVY.com. The American Headache Society recommends the use of Ajovy to prevent migraine headaches in adults who are unable to reduce their number of migraine days enough with other medications. This immune reaction caused their bodies to create antibodies against the drugs. Ajovy can be given on one of two different schedules: one 225-mg injection once per month, or three separate injections (total of 675 mg) once every three months. In clinical trials, there wasnt a significant difference in this side effect between people who took Ajovy monthly and those who took it once every three months. To date, long-term side effects havent been reported with Ajovy. It isnt known if Ajovy is safe to use during pregnancy. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Tell your healthcare provider about all the medicines you take and if you are pregnant, planning to become pregnant, or are breastfeeding. The medicine (120 mg) comes in a prefilled pen or syringe and is taken once a month. If youre thinking about having Ajovy treatment while youre breastfeeding, talk with your doctor about the possible benefits and risks. A monoclonal antibody is a kind of drug created from immune system cells. Also, do not leave it in direct sunlight or try to warm it up using a heat source such as hot water or a microwave. They can help you learn about other medications that might be right for you. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. How to use the autoinjector for AJOVY (fremanezumab-vfrm) injection. Take your filled sharps containers to a designated collection site. By preventing CGRP from attaching to its receptor, these three drugs help prevent vasodilation and inflammation. S.A.F.E. By stopping CGRP from working, Ajovy and Emgality help prevent vasodilation and inflammation in the brain. If prescribed the 675 mg dose, avoid injecting in exactly the same place. Biologic drugs are made from living cells. Such a reaction isnt common, but it is possible. (Keep in mind that Ajovy is used to help prevent migraine episodes.). Emgality comes as a single-dose prefilled syringe or pen. First, remove your autoinjector from the refrigerator and wait for 30 minutes to allow the medicine to reach room temperature. The cost with insurance will vary. The liver doesnt break down these drugs, as it does with most other drugs used to prevent migraine headaches. To avoid sticking yourself, dont recap the needle. By blocking CGRP, Ajovy and Aimovig help prevent vasodilation and inflammation. Do not stop taking Ajovy without first talking with your doctor. To request a mail-back container, please call our hotline at 1(888) CLEAN LA. If you forget or miss a dose, administer the dose as soon as you remember. Do not give this medicine to a child or adolescent under the age of 18 years. If you need financial support to pay for Ajovy, help is available. Check that the blue plunger has filled the viewing window and remove the autoinjector from the skin by lifting straight up. Now, wash your hands with soap and water and dry well with a clean towel. Insert the needle into the pinched skin at an angle of 45 to 90 degrees. A severe allergic reaction is the main serious side effect for Ajovy and Emgality. Other monoclonal antibodies are named in a similar way. Remove autoinjector 10 seconds after. The primary serious side effect for both Ajovy and Aimovig is a severe allergic reaction. In this article, well refer to Ajovys active drug as fremanezumab. Here are answers to some frequently asked questions about Ajovy. Ajovy is part of a new class of drugs known as calcitonin gene-related peptide (CGRP) antagonists. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. of Public Health Offices. To cause these effects in the brain, CGRP needs to bind (attach) to its receptors. Theyre also the main symptom of migraine, which is a neurological condition. the California Relay Service at 7-1-1. Ajovy is a brand-name prescription medication thats used to prevent migraine headaches in adults. Sharps that retract after use, or are very small, should be disposed of like all other sharps. Section 117671 of the California Health and Safety Code defines home-generated sharps waste as hypodermic needles, pen needles, intravenous needles, lancets, and other devices that are used to penetrate the skin for the delivery of medications derived from a household, including a multifamily residence or household. Botox is also an injection, but you receive it once every three months in your doctors office. AJOVY may cause allergic reactions, including itching, rash, and hives that can happen within hours and up to 1 month after receiving AJOVY. Programs Division. Chronic migraine headaches are the only condition that both Ajovy and Botox are used to prevent. The purpose of such expiration dates is to guarantee the effectiveness of the medication during this time. They can be safely stored in the refrigerator for up to 24 months, or until the expiration date listed on the container. The manufacturer of Ajovy provides patient stories from those whove taken this drug. You should not take Ajovy if you have a history of serious hypersensitivity reactions to Ajovy or any of its ingredients. Its not possible to copy these drugs exactly. As a prime member you can save on the price of your medicationshere at Amazon Pharmacy and at over 60,000 retail pharmacies. The FDA has approved Ajovy to help prevent migraine headaches in adults.